Beethoven is said to have been dealing with syphilis while writing some of his greatest masterpieces. He suffered from chronic illnesses, most of which went undiagnosed. Some believe his deafness was caused by the STD.
Abraham Lincoln is said to have contracted syphilis before he met his wife, Mary Todd, after sleeping with numerous prostitutes. He admitted to a close friend and biographer William Herndon that he had caught the STD.